There is an important need for non-medication interventions for depressed youth. The challenge is to develop an exercise intervention that can motivate a typically sedentary depressed adolescent to exercise on a regular basis. The goal is to demonstrate that exercise alone can provide an important and effective non-medication intervention for adolescent depression. This paper reports on the rationale and design of a pilot study which aims to inform the design of a larger trial to evaluate the efficacy of aerobic exercise to treat adolescent depression. After describing the case for exercise within the broader context of the prevalence of adolescent depression and other treatments, the paper describes the intervention and procedures for data collection. Major depressive disorder MDD is common in adolescents and results in significant morbidity and mortality Shaffer et al. With recent concerns about short and long-term safety with selective serotonin reuptake inhibitors SSRIs and other antidepressants, and poor overall response even when efficacy has been proven Emslie et al. It is also essential to evaluate whether such a non-medication treatment can provide further improvements in social, school, cognitive, and family functioning.
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DATE: Depressed adolescents treated with exercise: Study rationale and design for a pilot study
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The Depressed Adolescents Treated with Exercise (DATE) study evaluated a They had to be of normal intelligence (i.e., IQ > 70 based on the short WISC-III [Abstract] [Google Scholar]; Emslie GJ, Heiligenstein JH, Wagner KD, Hoog SL.
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